Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50014648
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578400(CHEMBL4862805 | US20240009175, Compound 50)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578402(CHEMBL4853889 | US20240009175, Compound 63)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578400(CHEMBL4862805 | US20240009175, Compound 50)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578402(CHEMBL4853889 | US20240009175, Compound 63)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578398(CHEMBL4859117 | US20240009175, Compound 35)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578397(CHEMBL4855352 | US20240009175, Compound 33)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578402(CHEMBL4853889 | US20240009175, Compound 63)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578399(CHEMBL4870878 | US20240009175, Compound 37)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578397(CHEMBL4855352 | US20240009175, Compound 33)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578400(CHEMBL4862805 | US20240009175, Compound 50)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578397(CHEMBL4855352 | US20240009175, Compound 33)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578398(CHEMBL4859117 | US20240009175, Compound 35)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578399(CHEMBL4870878 | US20240009175, Compound 37)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578399(CHEMBL4870878 | US20240009175, Compound 37)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578398(CHEMBL4859117 | US20240009175, Compound 35)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed