Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50015658
TargetHistone deacetylase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588303(CHEMBL5170036)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588302(CHEMBL5199116)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Rat)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588304(CHEMBL5202398)
Affinity DataIC50: 5nMAssay Description:Inhibition of rat HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531348(CHEMBL4456028)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using AMC-K(Ac)GL as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50322422(Largazole | CHEMBL1173445)
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531349(CHEMBL4451082)
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588308(CHEMBL5204304)
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588306(CHEMBL474318)
Affinity DataIC50: 30nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50: 36nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50: 47nMAssay Description:Inhibition of human HDAC2 expressed in HEK293T cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531334(CHEMBL472574)
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531324(CHEMBL4468518)
Affinity DataIC50: 56nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588305(CHEMBL5209235)
Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531349(CHEMBL4451082)
Affinity DataIC50: 65nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531348(CHEMBL4456028)
Affinity DataIC50: 67nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531324(CHEMBL4468518)
Affinity DataIC50: 83nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588309(CHEMBL470325)
Affinity DataIC50: 90nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 98nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588315(CHEMBL5197309)
Affinity DataIC50: 220nMAssay Description:Inhibition of HDAC1 in human MCF7 cells using TMB as substrate incubated for 2 hrs by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588307(CHEMBL451873)
Affinity DataIC50: 280nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588310(CHEMBL473512)
Affinity DataIC50: 330nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588315(CHEMBL5197309)
Affinity DataIC50: 430nMAssay Description:Inhibition of HDAC2 in human MCF7 cells using TMB as substrate incubated for 2 hrs by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50: 510nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588312(CHEMBL5203465)
Affinity DataIC50: 670nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588311(CHEMBL489280)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human HDAC6 expressed in HEK293T cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTubulin beta-3 chain(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588315(CHEMBL5197309)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of beta-tubulin polymerization in human MCF7 cells using TMB as substrate incubated for 2 hrs by spectrophotometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using AMC-K(Ac)GL as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50322422(Largazole | CHEMBL1173445)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50079401(Sodium butyrate | CHEMBL62381 | butanoate | butyra...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant His-tagged HDAC3 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50079401(Sodium butyrate | CHEMBL62381 | butanoate | butyra...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant full-length His-tagged HDAC2 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50079401(Sodium butyrate | CHEMBL62381 | butanoate | butyra...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant His-tagged HDAC8 expressed in Escherichia coli incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50079401(Sodium butyrate | CHEMBL62381 | butanoate | butyra...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant His-tagged HDAC1 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588313(CHEMBL5179307)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed