Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50016608
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50596052(CHEMBL5196484)
Affinity DataKd:  28nMAssay Description:Binding affinity to FTO (unknown origin) assessed as dissociation constant at 180 uM by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50596052(CHEMBL5196484)
Affinity DataIC50: 87nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50596051(CHEMBL5183243)
Affinity DataIC50: 570nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50596053(CHEMBL5173876)
Affinity DataIC50: 930nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRNA demethylase ALKBH5(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50596051(CHEMBL5183243)
Affinity DataIC50: 7.13E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin) demethylation activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50596052(CHEMBL5196484)
Affinity DataIC50: 8.98E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin) demethylation activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed