Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50014903
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 54nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580924(CHEMBL5090940)
Affinity DataIC50: 63nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580923(CHEMBL5078131)
Affinity DataIC50: 66nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580925(CHEMBL5091589)
Affinity DataIC50: 78nMAssay Description:Displacement of fluorescent estradiol from full-length ERalpha (unknown origin) measured after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataIC50: 89nMAssay Description:Displacement of fluorescent estradiol from full-length ERalpha (unknown origin) measured after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580924(CHEMBL5090940)
Affinity DataIC50: 91nMAssay Description:Displacement of fluorescent estradiol from full-length ERalpha (unknown origin) measured after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580927(CHEMBL5091622)
Affinity DataIC50: 96nMAssay Description:Displacement of fluorescent estradiol from full-length ERalpha (unknown origin) measured after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580923(CHEMBL5078131)
Affinity DataIC50: 102nMAssay Description:Displacement of fluorescent estradiol from full-length ERalpha (unknown origin) measured after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580926(CHEMBL5085006)
Affinity DataIC50: 132nMAssay Description:Displacement of fluorescent estradiol from full-length ERalpha (unknown origin) measured after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 139nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580925(CHEMBL5091589)
Affinity DataIC50: 175nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580924(CHEMBL5090940)
Affinity DataIC50: 582nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580924(CHEMBL5090940)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed