Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50015439
TargetP2X purinoceptor 7(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50586608(CHEMBL5083184)
Affinity DataKd:  710nMAssay Description:Binding affinity to human wild type P2X7R assessed as dissociation constant by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50234965(A-740003 | N-(1-{[(Cyanoimino)(5-quinolinylamino)m...)
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human P2X7R expressed in differentiated human THP-1 cells assessed as reduction in BzATP induced YO-PRO uptake by cells incuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50234965(A-740003 | N-(1-{[(Cyanoimino)(5-quinolinylamino)m...)
Affinity DataIC50: 156nMAssay Description:Antagonist activity at human P2X7R expressed in differentiated human THP-1 cells assessed as reduction in BzATP induced IL-1beta release incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed