Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50003716
TargetC-X-C chemokine receptor type 2(Human)
University of Perugia Via Del Liceo

Curated by ChEMBL
LigandPNGBDBM50187004(3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CXCR2 (unknown origin)More data for this Ligand-Target Pair
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PubMed
TargetC-X-C chemokine receptor type 2(Human)
University of Perugia Via Del Liceo

Curated by ChEMBL
LigandPNGBDBM50200880(2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5-methylfuran...)
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at CXCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
University of Perugia Via Del Liceo

Curated by ChEMBL
LigandPNGBDBM50200880(2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5-methylfuran...)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at CXCR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Perugia Via Del Liceo

Curated by ChEMBL
LigandPNGBDBM50022802(CHEMBL2046866)
Affinity DataKi:  3.30nMAssay Description:Displacement of 125I-PYY from human neuropeptide Y Y1 receptor expressed in human SK-N-MC cell membrane assessed as inhibition constant incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNeuropeptide Y receptor type 1(Human)
University of Perugia Via Del Liceo

Curated by ChEMBL
LigandPNGBDBM50022803(CHEMBL5288617)
Affinity DataKi:  5.10nMAssay Description:Displacement of 125I-PYY from human neuropeptide Y Y1 receptor expressed in human SK-N-MC cell membrane assessed as inhibition constant incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 1(Human)
University of Perugia Via Del Liceo

Curated by ChEMBL
LigandPNGBDBM50429537(CHEMBL2333770)
Affinity DataKi:  6nMAssay Description:Antagonist activity at human P2Y1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
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PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
University of Perugia Via Del Liceo

Curated by ChEMBL
LigandPNGBDBM129261(US8815951, 297)
Affinity DataKi:  7nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase (unknown origin) using [3H]1,3-diphenyl-trans-propene oxide as substrate assessed as inhibition c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Perugia Via Del Liceo

Curated by ChEMBL
LigandPNGBDBM50120392(CHEMBL5282574)
Affinity DataKi:  21nMAssay Description:Displacement of 125I-PYY from human neuropeptide Y Y1 receptor expressed in human SK-N-MC cell membrane assessed as inhibition constant incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Perugia Via Del Liceo

Curated by ChEMBL
LigandPNGBDBM50056299(CHEMBL5288434)
Affinity DataKi:  99nMAssay Description:Displacement of 125I-PYY from human neuropeptide Y Y1 receptor expressed in human SK-N-MC cell membrane assessed as inhibition constant incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed