Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50014302
Affinity DataIC50: 2.40nMAssay Description:Inhibition of CYP3A4 (unknown origin) using BOMCC as a substrate incubated for 20 mins by fluorescence based analysisMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of ErbB4 in human T47D cells assessed as suppression of neuregulin 1-induced autophosphorylation incubated for 90 mins by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting meth...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of ErbB4 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of ErbB4 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human ERG incubated for 3 hrs by competitive fluorescence tracer binding based assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetEpidermal growth factor receptor(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of JNK3 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of ErbB4 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of ErbB4 in human T47D cells assessed as suppression of neuregulin 1-induced autophosphorylation incubated for 90 mins by sandwich ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of EGFR- T790M mutant (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting met...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Inhibition of KDR (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type B-RAF (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of FLT-3(unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting meth...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of RAF1 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 3.25E+3nMAssay Description:Inhibition of MEK2 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of EGFR- L861Q mutant (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting met...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of JNK3 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase A-Raf(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 7.06E+3nMAssay Description:Inhibition of A-RAF (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8.31E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) using EOMCC as a substrate incubated for 20 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.35E+3nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 8.56E+3nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation countin...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 9.92E+3nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human ERG incubated for 3 hrs by competitive fluorescence tracer binding based assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of human ERG incubated for 3 hrs by competitive fluorescence tracer binding based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using BOMCC as a substrate incubated for 20 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using BOMCC as a substrate incubated for 20 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) using EOMCC as a substrate incubated for 20 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) using EOMCC as a substrate incubated for 20 mins by fluorescence based analysisMore data for this Ligand-Target Pair
