Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50017974
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606639(CHEMBL5219016)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606640(CHEMBL5220467)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606641(CHEMBL5219752)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606645(CHEMBL5220455)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606638(CHEMBL5220113)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606644(CHEMBL5219791)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606635(CHEMBL5220820)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606650(CHEMBL5219058)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606637(CHEMBL5220002)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606634(CHEMBL5220229)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606636(CHEMBL5220778)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606643(CHEMBL5218653)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606642(CHEMBL5220060)
Affinity DataIC50: 4nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606648(CHEMBL5220622)
Affinity DataIC50: 24nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606646(CHEMBL5221023)
Affinity DataIC50: 33nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 115nMAssay Description:Inhibition of human alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measure...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 333nMAssay Description:Inhibition of rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606647(CHEMBL5220652)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606649(CHEMBL5219354)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606651(CHEMBL5219320)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rat)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and meas...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha2beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and me...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential a...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha6/alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Rat)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat alpha4beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and meas...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha4beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and me...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat alpha4beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and meas...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha4beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and me...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and meas...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and me...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and me...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-4(Rat)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat alpha2beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and meas...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-4(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha2beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and me...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Rat)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat alpha2beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and meas...More data for this Ligand-Target Pair
In DepthDetails
PubMed