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Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50014870
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM363080(US9850225, Example 1016 | (R)-2-((2-((3-cyanobenzy...)
Affinity DataEC50:  2.08E+3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in human Jurkat cells expressing PD-1/NFAT/Luc cocultured with CHO-K1 cells expressing PD-L1/aAPC assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580530(CHEMBL5092744)
Affinity DataKd:  3.30nMAssay Description:Binding affinity to human PD-L1 assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in human Jurkat cells expressing PD-1/NFAT/Luc cocultured with CHO-K1 cells expressing PD-L1/aAPC assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580530(CHEMBL5092744)
Affinity DataEC50:  375nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in human Jurkat cells expressing PD-1/NFAT/Luc cocultured with CHO-K1 cells expressing PD-L1/aAPC assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580530(CHEMBL5092744)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580548(CHEMBL5081629)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580531(CHEMBL5086579)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580532(CHEMBL5081208)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580538(CHEMBL5089213)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580544(CHEMBL5082639)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580534(CHEMBL5093300)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580543(CHEMBL5077123)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580535(CHEMBL5069508)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580549(CHEMBL5094163)
Affinity DataIC50: 13nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580556(CHEMBL5091570)
Affinity DataIC50: 15nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580557(CHEMBL5076462)
Affinity DataIC50: 16nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580529(CHEMBL5092891)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580563(CHEMBL5079158)
Affinity DataIC50: 22nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580551(CHEMBL5087916)
Affinity DataIC50: 24nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580545(CHEMBL5075064)
Affinity DataIC50: 24nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580550(CHEMBL5084706)
Affinity DataIC50: 27nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580533(CHEMBL5088657)
Affinity DataIC50: 28nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580546(CHEMBL5087535)
Affinity DataIC50: 31nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580552(CHEMBL5081726)
Affinity DataIC50: 31nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580524(CHEMBL5090292)
Affinity DataIC50: 34nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580560(CHEMBL5092191)
Affinity DataIC50: 34nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM363080(US9850225, Example 1016 | (R)-2-((2-((3-cyanobenzy...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580553(CHEMBL5079880)
Affinity DataIC50: 52nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580537(CHEMBL5075291)
Affinity DataIC50: 56nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580558(CHEMBL5071084)
Affinity DataIC50: 57nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580539(CHEMBL5090380)
Affinity DataIC50: 59nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580542(CHEMBL5092015)
Affinity DataIC50: 61nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580541(CHEMBL5084021)
Affinity DataIC50: 101nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580559(CHEMBL5084057)
Affinity DataIC50: 130nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580540(CHEMBL5093484)
Affinity DataIC50: 162nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580526(CHEMBL5086179)
Affinity DataIC50: 206nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580562(CHEMBL5075170)
Affinity DataIC50: 291nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580561(CHEMBL5077414)
Affinity DataIC50: 342nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580564(CHEMBL5093718)
Affinity DataIC50: 393nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580547(CHEMBL5093287)
Affinity DataIC50: 426nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580536(CHEMBL5083609)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580554(CHEMBL5082398)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580528(CHEMBL5085728)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580565(CHEMBL5088893)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580525(CHEMBL5084418)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580527(CHEMBL5089057)
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580555(CHEMBL5080903)
Affinity DataIC50: 3.59E+3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580530(CHEMBL5092744)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed