Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50018643
TargetCREB-binding protein(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM449844(1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...)
Affinity DataKd:  19nMAssay Description:Binding affinity to CBP (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone acetyltransferase p300(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM449844(1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...)
Affinity DataKd:  31nMAssay Description:Binding affinity to EP300 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM449844(1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...)
Affinity DataKd:  7.10nMAssay Description:Binding affinity BRD4 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM449844(1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...)
Affinity DataKd:  3.5nMAssay Description:Binding affinity BRD3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM449844(1,3-dimethyl-5-[2-tetrahydropyran-4-yl-3-[2-(trifl...)
Affinity DataKd:  9nMAssay Description:Binding affinity BRD2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50610594(CHEMBL5290398)
Affinity DataKd:  385nMAssay Description:Binding affinity to LSD1 (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataKd:  243nMAssay Description:Binding affinity to LSD1 (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50610593(CHEMBL5265827)
Affinity DataKd:  2.10nMAssay Description:Binding affinity to BRD4 BD2 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataKd:  230nMAssay Description:Binding affinity to BRD4 BD2 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50610593(CHEMBL5265827)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50587649(CHEMBL5197137)
Affinity DataKd:  69nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataKd:  51nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataKd:  90nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 11nMAssay Description:Inhibition of BRD4 BD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 74nMAssay Description:Inhibition of BRD4 BD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50180980(CHEMBL3818594)
Affinity DataIC50: 150nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human LSD1 (unknown orgin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)
Affinity DataIC50: 180nMAssay Description:Inhibition of human LSD1 (unknown orgin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50610592(CHEMBL5272967)
Affinity DataIC50: 210nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50180981(CHEMBL3818026)
Affinity DataIC50: 270nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50503631(CHEMBL4436792)
Affinity DataIC50: 280nMAssay Description:Inhibition of human LSD1 (unknown orgin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50587649(CHEMBL5197137)
Affinity DataIC50: 290nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetREST corepressor 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50610592(CHEMBL5272967)
Affinity DataIC50: 330nMAssay Description:Inhibition of human N-terminal GST-tagged LSD1 expressed in Escherichia coli using ARTK (Me)-2QTARKSTGGKAPRKQLA as substrate/FLAG-tagged CoREST trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 370nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 400nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 570nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 600nMAssay Description:Inhibition of human LSD1 (unknown orgin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50180980(CHEMBL3818594)
Affinity DataIC50: 670nMAssay Description:Inhibition of BRD4 BD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 729nMAssay Description:Inhibition of BRD4 BD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50180981(CHEMBL3818026)
Affinity DataIC50: 850nMAssay Description:Inhibition of BRD4 BD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 960nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human LSD1 (unknown orgin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of human LSD1 (unknown orgin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569835(CHEMBL4850917)
Affinity DataIC50: 5.73E+3nMAssay Description:Inhibition of HDAC in human K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569835(CHEMBL4850917)
Affinity DataIC50: 7.14E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50569835(CHEMBL4850917)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of HDAC in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50610594(CHEMBL5290398)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of human LSD1 (unknown orgin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50503631(CHEMBL4436792)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed