Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50018767
LigandPNGBDBM50261009(3-(3-Chloro-4'-ethanesulfonyl-biphenyl-4-yl)-5-[1-...)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50260880(3-(3-Chloro-biphenyl-4-yl)-5-[1-(4-chloro-phenyl)-...)
Affinity DataEC50:  1.70E+3nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50612251(CHEMBL371463 | CHEBI:35065)
Affinity DataEC50:  1.40E+4nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50612250(PRETILACHLOR | CHEBI:34931)
Affinity DataEC50:  490nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50359941(OXADIAZON)
Affinity DataEC50:  900nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50106148(5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]...)
Affinity DataEC50:  1.50E+4nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50612249(CHEMBL5283048)
Affinity DataEC50:  1.30E+4nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50612248(CHEMBL5271650)
Affinity DataEC50:  7.10E+3nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM31774(cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...)
Affinity DataEC50:  2.70E+3nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50612247(CHEMBL5283219)
Affinity DataEC50:  1.50E+4nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50261050(3-(3-Chloro-3'-ethanesulfonyl-biphenyl-4-yl)-5-[1-...)
Affinity DataEC50:  2.50E+4nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50261010(3-(3-Chloro-2'-ethanesulfonyl-biphenyl-4-yl)-5-[1-...)
Affinity DataEC50:  700nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50370232(BA-41166E | L-5103 | Rifadin | Rifampicin | RIFAMP...)
Affinity DataEC50:  1.19E+3nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM429615(US10550091, No. LC-24 | US10947203, No. LC-24)
Affinity DataEC50:  880nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50436260(CHEMBL2398717)
Affinity DataEC50:  500nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50463434(CHEMBL3781118)
Affinity DataEC50:  8nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50030477(CHEBI:77317 | SR-12813 | CHEMBL458767)
Affinity DataEC50:  220nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50193079(CHEMBL1237210 | CHEBI:5834)
Affinity DataEC50:  40nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50261050(3-(3-Chloro-3'-ethanesulfonyl-biphenyl-4-yl)-5-[1-...)
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50261010(3-(3-Chloro-2'-ethanesulfonyl-biphenyl-4-yl)-5-[1-...)
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50260880(3-(3-Chloro-biphenyl-4-yl)-5-[1-(4-chloro-phenyl)-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50261009(3-(3-Chloro-4'-ethanesulfonyl-biphenyl-4-yl)-5-[1-...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM429615(US10550091, No. LC-24 | US10947203, No. LC-24)
Affinity DataIC50: 750nMAssay Description:Binding affinity to human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed