Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50015621
TargetTransitional endoplasmic reticulum ATPase(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50587862(CHEMBL5206855)
Affinity DataIC50: 7nMAssay Description:Inhibition of p97 (unknown origin) in presence of ATP by Biomol Green Reagent based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransitional endoplasmic reticulum ATPase(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50514004(CHEMBL4476693)
Affinity DataIC50: 8nMAssay Description:Inhibition of p97 (unknown origin) in presence of ATP by Biomol Green Reagent based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransitional endoplasmic reticulum ATPase(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50500325(Cb 5083 | Cb-5083)
Affinity DataIC50: 11nMAssay Description:Inhibition of p97 (unknown origin) incubated for 15 mins in presence of ATP by ADP Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpastin(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50587865(CHEMBL5190401)
Affinity DataIC50: 99nMAssay Description:Inhibition of human Spastin in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetVacuolar protein sorting-associated protein 4B(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50514006(CHEMBL4572843)
Affinity DataIC50: 710nMAssay Description:Inhibition of recombinant VPS4B (unknown origin) expressed in Escherichia coli (DE3) incubated for 10 mins by malachite green based ATPase assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTransitional endoplasmic reticulum ATPase(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50237614(CHEBI:465284 | BW-759U | Cymevene | Cytovene | Gan...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of p97 (unknown origin) incubated for 15 mins in presence of ATP by ADP Glo assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpastin(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50587864(CHEMBL5201542)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human Spastin in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpastin(Fruit fly)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50587863(CHEMBL5193085)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of wild-type Drosophila melanogaster Spastin (209 to 758 residues) in presence of ATP by NADH-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetTransitional endoplasmic reticulum ATPase(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50514006(CHEMBL4572843)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant p97 (unknown origin) expressed in Escherichia coli (DE3) incubated for 30 mins by malachite green based ATPase assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetEukaryotic translation initiation factor 4 gamma 2(Mouse)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM46584(SMR000434303 | N*2*,N*4*-Dibenzyl-quinazoline-2,4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse p97 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGem-associated protein 4(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50587861(DEHYDROCURVULARIN | Dehydrocurvularin | Trans-Dehy...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins followed by ATP addition measured for 30 to 120 ...More data for this Ligand-Target Pair
In DepthDetails
PubMed