Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50013593
TargetGlutamate carboxypeptidase 2(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM17759(pentanedioic acid analogue, (S)-1 | (2S)-2-(phosph...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of GCPII (unknown origin) NAALADase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50102258((S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-ureido]-...)
Affinity DataKi:  8nMAssay Description:Inhibition of human GCPII expressed in CHO cells assessed as accumulation of glutamate using NAAG as substrate by e Amplex Red glutamic acid assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM17759(pentanedioic acid analogue, (S)-1 | (2S)-2-(phosph...)
Affinity DataIC50: 94nMAssay Description:Inhibition of GCPII (unknown origin) expressed in DU-145 cells after 2 hrs by Amplex red reagent based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50102258((S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-ureido]-...)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of GCPII (unknown origin) expressed in DU-145 cells after 2 hrs by Amplex red reagent based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50567950(CHEMBL4870708)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of GCPII (unknown origin) expressed in DU-145 cells after 2 hrs by Amplex red reagent based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed