Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50002694
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023707(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataIC50: 63nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) in mouse L1210 leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023705(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataIC50: 67nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) in mouse L1210 leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023708(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataIC50: 83nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) in mouse L1210 leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023706(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataIC50: 550nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) in mouse L1210 leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023710(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataKi:  4.50E+4nMAssay Description:Inhibition of Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023709(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  1.85E+5nMAssay Description:Inhibition of Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023711(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  1.88E+5nMAssay Description:Inhibition of Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed