Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50013572
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM139295(US8614223, 73 | US10858323, Compound 1)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal GST-tagged full-length human HDAC6 expressed in Sf9 infected baculovirus system using FTS as substrate preincubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567694(CHEMBL4858994)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM417049(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant human full-length HDAC6 using RHKK(Ac)AMC as substrate preincubated for 5 to 10 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567706(CHEMBL4854123)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567693(CHEMBL4873296)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567692(CHEMBL4847454)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567705(CHEMBL4858810)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM139323(US8614223, 101)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of N-terminal GST-tagged full-length human HDAC6 expressed in Sf9 infected baculovirus system using FTS as substrate preincubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567707(CHEMBL4875748)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567709(CHEMBL4854768)
Affinity DataIC50: 12nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567695(CHEMBL4876815)
Affinity DataIC50: 13nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567702(CHEMBL4875969)
Affinity DataIC50: 14nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567708(CHEMBL4860396)
Affinity DataIC50: 14nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567703(CHEMBL4862139)
Affinity DataIC50: 19nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal GST-tagged full-length human HDAC6 expressed in Sf9 infected baculovirus system using FTS as substrate preincubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567699(CHEMBL4871812)
Affinity DataIC50: 22nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567696(CHEMBL4858918)
Affinity DataIC50: 29nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567701(CHEMBL4856735)
Affinity DataIC50: 37nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567704(CHEMBL4857891)
Affinity DataIC50: 43nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567710(CHEMBL4862419)
Affinity DataIC50: 45nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567691(CHEMBL4853358)
Affinity DataIC50: 100nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567698(CHEMBL4854716)
Affinity DataIC50: 111nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567711(CHEMBL4878252)
Affinity DataIC50: 129nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567695(CHEMBL4876815)
Affinity DataIC50: 166nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567694(CHEMBL4858994)
Affinity DataIC50: 254nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567690(CHEMBL4848981)
Affinity DataIC50: 255nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567706(CHEMBL4854123)
Affinity DataIC50: 257nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567705(CHEMBL4858810)
Affinity DataIC50: 277nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567707(CHEMBL4875748)
Affinity DataIC50: 294nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567708(CHEMBL4860396)
Affinity DataIC50: 295nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567697(CHEMBL4849884)
Affinity DataIC50: 318nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567693(CHEMBL4873296)
Affinity DataIC50: 367nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567709(CHEMBL4854768)
Affinity DataIC50: 377nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567698(CHEMBL4854716)
Affinity DataIC50: 385nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567692(CHEMBL4847454)
Affinity DataIC50: 392nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567704(CHEMBL4857891)
Affinity DataIC50: 400nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567702(CHEMBL4875969)
Affinity DataIC50: 406nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567696(CHEMBL4858918)
Affinity DataIC50: 431nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567700(CHEMBL4849225)
Affinity DataIC50: 497nMAssay Description:Inhibition of human HDAC6 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567699(CHEMBL4871812)
Affinity DataIC50: 502nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567710(CHEMBL4862419)
Affinity DataIC50: 509nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567711(CHEMBL4878252)
Affinity DataIC50: 706nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567703(CHEMBL4862139)
Affinity DataIC50: 761nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567697(CHEMBL4849884)
Affinity DataIC50: 798nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567690(CHEMBL4848981)
Affinity DataIC50: 804nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50567701(CHEMBL4856735)
Affinity DataIC50: 819nMAssay Description:Inhibition of human HDAC1 preincubated for 15 mins followed by substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
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