Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50015492
TargetBcl-2-related protein A1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587033(CHEMBL5075478)
Affinity DataIC50: 18nMAssay Description:Inhibition of human Bfl-1 (1 to 149 residues) expressed in Rosetta-gami (DE3) using biotinylated-BH3 peptide as substrate measured after 2 hrs by DEL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587037(CHEMBL5082279)
Affinity DataIC50: 19nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587033(CHEMBL5075478)
Affinity DataIC50: 22nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587036(CHEMBL5091695)
Affinity DataIC50: 23nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587038(CHEMBL5090086)
Affinity DataIC50: 24nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587035(CHEMBL5094351)
Affinity DataIC50: 94nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBcl-2-related protein A1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587038(CHEMBL5090086)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Bfl-1 (1 to 149 residues) expressed in Rosetta-gami (DE3) using biotinylated-BH3 peptide as substrate measured after 2 hrs by DEL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587048(CHEMBL5074275)
Affinity DataIC50: 261nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587049(CHEMBL5094645)
Affinity DataIC50: 313nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBcl-2-related protein A1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587036(CHEMBL5091695)
Affinity DataIC50: 400nMAssay Description:Inhibition of human Bfl-1 (1 to 149 residues) expressed in Rosetta-gami (DE3) using biotinylated-BH3 peptide as substrate measured after 2 hrs by DEL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587034(CHEMBL5090130)
Affinity DataIC50: 570nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBcl-2-related protein A1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587037(CHEMBL5082279)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Bfl-1 (1 to 149 residues) expressed in Rosetta-gami (DE3) using biotinylated-BH3 peptide as substrate measured after 2 hrs by DEL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587042(CHEMBL5085592)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587044(CHEMBL5089925)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587043(CHEMBL5092008)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587046(CHEMBL5085661)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587045(CHEMBL5079420)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587039(CHEMBL5092376)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587047(CHEMBL5081259)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587040(CHEMBL5072408)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBcl-2-related protein A1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587035(CHEMBL5094351)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human Bfl-1 (1 to 149 residues) expressed in Rosetta-gami (DE3) using biotinylated-BH3 peptide as substrate measured after 2 hrs by DEL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBcl-2-related protein A1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587034(CHEMBL5090130)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Bfl-1 (1 to 149 residues) expressed in Rosetta-gami (DE3) using biotinylated-BH3 peptide as substrate measured after 2 hrs by DEL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587041(CHEMBL5076122)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Mcl-1 (179 to 323 residues) expressed in Escherichia coli BL21 using biotinylated-BH3 peptide as substrate measured after 2 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587038(CHEMBL5090086)
Affinity DataKi:  17nMAssay Description:Inhibition of human Mcl-1 assessed as inhibition constant by DELFIA displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50587037(CHEMBL5082279)
Affinity DataKi:  37nMAssay Description:Inhibition of human Mcl-1 assessed as inhibition constant by DELFIA displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed