Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50013571
TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567687(CHEMBL4865410)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to wild-type human partial length MKK4 (S84 to D399 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567686(CHEMBL4798975)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to wild-type human partial length MKK4 (S84 to D399 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 5(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567687(CHEMBL4865410)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to wild-type human partial length MAP4K5 (M1 to P297 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567687(CHEMBL4865410)
Affinity DataKd:  9.5nMAssay Description:Binding affinity to wild-type human partial length ZAK (M1 to L331 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567689(CHEMBL4790247)
Affinity DataIC50: 29nMAssay Description:Inhibition of MKK4 (unknown origin) by PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567688(CHEMBL4784779)
Affinity DataIC50: 89nMAssay Description:Inhibition of MKK4 (unknown origin) by PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567687(CHEMBL4865410)
Affinity DataKd:  140nMAssay Description:Binding affinity to wild-type human full length JNK1 (M1 to Q384 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567686(CHEMBL4798975)
Affinity DataIC50: 146nMAssay Description:Inhibition of MKK4 (unknown origin) by PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567686(CHEMBL4798975)
Affinity DataKd:  210nMAssay Description:Binding affinity to wild-type human full length JNK1 (M1 to Q384 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567686(CHEMBL4798975)
Affinity DataKd:  450nMAssay Description:Binding affinity to wild-type human partial length BRAF (S429 to E741 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567687(CHEMBL4865410)
Affinity DataKd:  610nMAssay Description:Binding affinity to wild-type human partial length BRAF (S429 to E741 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 5(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567686(CHEMBL4798975)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to wild-type human partial length MAP4K5 (M1 to P297 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567686(CHEMBL4798975)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to wild-type human full length MKK7 (M1 to R419 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567687(CHEMBL4865410)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to wild-type human full length MKK7 (M1 to R419 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Eberhard Karls Universit£T

Curated by ChEMBL
LigandPNGBDBM50567686(CHEMBL4798975)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to wild-type human partial length ZAK (M1 to L331 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed