Compile Data Set for Download or QSAR
Report error Found 103 Enz. Inhib. hit(s) with all data for entry = 50013986
LigandPNGBDBM50571459(CHEMBL4872830)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to VPS34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571464(CHEMBL4874640 | US11685734, Example 43)
Affinity DataKd:  4.60E+3nMAssay Description:Binding affinity to mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571476(CHEMBL4852400 | US11685734, Example 215)
Affinity DataIC50: 90nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571471(CHEMBL4858310 | US11685734, Example 213)
Affinity DataIC50: 130nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571463(CHEMBL4862803)
Affinity DataIC50: 150nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571467(CHEMBL4850755)
Affinity DataIC50: 200nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571459(CHEMBL4872830)
Affinity DataIC50: 230nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571464(CHEMBL4874640 | US11685734, Example 43)
Affinity DataIC50: 290nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571474(CHEMBL4857803 | US11685734, Example 211)
Affinity DataIC50: 450nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571466(CHEMBL4878312)
Affinity DataIC50: 500nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571473(CHEMBL4856420 | US11685734, Example 39)
Affinity DataIC50: 520nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571472(CHEMBL4867495 | US11685734, Example 291)
Affinity DataIC50: 560nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571469(CHEMBL4852763 | US11685734, Example 270)
Affinity DataIC50: 820nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571446(CHEMBL4879094)
Affinity DataIC50: 880nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571460(CHEMBL4858974 | US11685734, Example 98)
Affinity DataIC50: 920nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571470(CHEMBL4869283 | US11685734, Example 41)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50550657(CHEMBL4792737)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571461(CHEMBL4866506 | US11685734, Example 96)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571475(CHEMBL4853948 | US11685734, Example 292)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571468(CHEMBL4845919)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571458(CHEMBL4846084 | US11685734, Example 35)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571455(CHEMBL4873212 | US11685734, Example 1)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571462(CHEMBL4849786 | US11685734, Example 88)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571454(CHEMBL4873551)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571476(CHEMBL4852400 | US11685734, Example 215)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of ATR in human HT-29 cells assessed as reduction in CHK1 phosphorylation incubated for 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571452(CHEMBL4874992)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571458(CHEMBL4846084 | US11685734, Example 35)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of ATR in human HT-29 cells assessed as reduction in CHK1 phosphorylation incubated for 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571473(CHEMBL4856420 | US11685734, Example 39)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of ATR in human HT-29 cells assessed as reduction in CHK1 phosphorylation incubated for 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571447(CHEMBL4872413)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571448(CHEMBL4872482)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571449(CHEMBL4853674)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571450(CHEMBL4850102)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571451(CHEMBL4851148)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571453(CHEMBL4868624)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571456(CHEMBL4851518)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571457(CHEMBL4854138)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571465(CHEMBL4852165)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571459(CHEMBL4872830)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATR in human HT-29 cells assessed as reduction in CHK1 phosphorylation incubated for 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571464(CHEMBL4874640 | US11685734, Example 43)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ATR in human HT-29 cells assessed as reduction in CHK1 phosphorylation incubated for 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571467(CHEMBL4850755)
Affinity DataKi:  0.100nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571471(CHEMBL4858310 | US11685734, Example 213)
Affinity DataKi:  0.200nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571463(CHEMBL4862803)
Affinity DataKi:  0.300nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571476(CHEMBL4852400 | US11685734, Example 215)
Affinity DataKi:  0.400nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50550657(CHEMBL4792737)
Affinity DataKi:  0.5nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571474(CHEMBL4857803 | US11685734, Example 211)
Affinity DataKi:  0.600nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571475(CHEMBL4853948 | US11685734, Example 292)
Affinity DataKi:  0.900nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571459(CHEMBL4872830)
Affinity DataKi:  1nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571466(CHEMBL4878312)
Affinity DataKi:  1nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571468(CHEMBL4845919)
Affinity DataKi:  1nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Charles River

Curated by ChEMBL
LigandPNGBDBM50571469(CHEMBL4852763 | US11685734, Example 270)
Affinity DataKi:  1nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
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