Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50012428
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557561(CHEMBL4790721)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557559(CHEMBL4753667)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557563(CHEMBL4746688)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557560(CHEMBL4760438)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557558(CHEMBL4747513)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human N-terminal GST-fused ALK L1196M mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557559(CHEMBL4753667)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human N-terminal GST-fused ALK L1196M mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557561(CHEMBL4790721)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human N-terminal GST-fused ALK L1196M mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557558(CHEMBL4747513)
Affinity DataIC50: 4nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557560(CHEMBL4760438)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human N-terminal GST-fused ALK L1196M mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557562(CHEMBL4743188)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557563(CHEMBL4746688)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human N-terminal GST-fused ALK L1196M mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557561(CHEMBL4790721)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human N-terminal GST-fused ALK G1202R mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557559(CHEMBL4753667)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human N-terminal GST-fused ALK G1202R mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557560(CHEMBL4760438)
Affinity DataIC50: 7nMAssay Description:Inhibition of human N-terminal GST-fused ALK G1202R mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557562(CHEMBL4743188)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human N-terminal GST-fused ALK G1202R mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human N-terminal GST-fused ALK L1196M mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557558(CHEMBL4747513)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human N-terminal GST-fused ALK G1202R mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557562(CHEMBL4743188)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of human N-terminal GST-fused ALK L1196M mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557563(CHEMBL4746688)
Affinity DataIC50: 13nMAssay Description:Inhibition of human N-terminal GST-fused ALK G1202R mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 86nMAssay Description:Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557563(CHEMBL4746688)
Affinity DataIC50: 103nMAssay Description:Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557560(CHEMBL4760438)
Affinity DataIC50: 135nMAssay Description:Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 172nMAssay Description:Inhibition of human N-terminal GST-fused ALK G1202R mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus infected Sf21 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557562(CHEMBL4743188)
Affinity DataIC50: 186nMAssay Description:Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557558(CHEMBL4747513)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557559(CHEMBL4753667)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557561(CHEMBL4790721)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus infected Sf21 insect cells using Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557558(CHEMBL4747513)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells using Sr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557559(CHEMBL4753667)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells using Sr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557560(CHEMBL4760438)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells using Sr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557561(CHEMBL4790721)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells using Sr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557562(CHEMBL4743188)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells using Sr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50557563(CHEMBL4746688)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells using Sr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Cancer Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells using Sr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed