Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50013158
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate measured after 1 hr by ADP-glo assayMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human PI3Kalpha using PIP2 as substrate incubated for 1 hr by kinase-glo luminescent assayMore data for this Ligand-Target Pair
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PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiaxing University

Curated by ChEMBL
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end amino acids) using ULight-4E-BP1 as substrate incubated for 1 hr by LANCE Ul...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of recombinant human full-length His-tagged PI3Kgamma expressed in baculovirus expression system using PIP2 as substrate measured after 1 ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50563252(CHEMBL4739883)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate measured after 1 hr by ADP-glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate measured after 1 hr by ADP-glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563252(CHEMBL4739883)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human PI3Kalpha using PIP2 as substrate incubated for 1 hr by kinase-glo luminescent assayMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50563248(CHEMBL4789813)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human PI3Kalpha using PIP2 as substrate incubated for 1 hr by kinase-glo luminescent assayMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50563251(CHEMBL4758904)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human PI3Kalpha using PIP2 as substrate incubated for 1 hr by kinase-glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563250(CHEMBL4787768)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human PI3Kalpha using PIP2 as substrate incubated for 1 hr by kinase-glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563252(CHEMBL4739883)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate measured after 1 hr by ADP-glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563252(CHEMBL4739883)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human full-length His-tagged PI3Kgamma expressed in baculovirus expression system using PIP2 as substrate measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563253(CHEMBL4750601)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human PI3Kalpha using PIP2 as substrate incubated for 1 hr by kinase-glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563249(CHEMBL4741551)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human PI3Kalpha using PIP2 as substrate incubated for 1 hr by kinase-glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiaxing University

Curated by ChEMBL
LigandPNGBDBM50563249(CHEMBL4741551)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end amino acids) using ULight-4E-BP1 as substrate incubated for 1 hr by LANCE Ul...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiaxing University

Curated by ChEMBL
LigandPNGBDBM50563250(CHEMBL4787768)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end amino acids) using ULight-4E-BP1 as substrate incubated for 1 hr by LANCE Ul...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiaxing University

Curated by ChEMBL
LigandPNGBDBM50563248(CHEMBL4789813)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end amino acids) using ULight-4E-BP1 as substrate incubated for 1 hr by LANCE Ul...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiaxing University

Curated by ChEMBL
LigandPNGBDBM50563251(CHEMBL4758904)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end amino acids) using ULight-4E-BP1 as substrate incubated for 1 hr by LANCE Ul...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiaxing University

Curated by ChEMBL
LigandPNGBDBM50563252(CHEMBL4739883)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end amino acids) using ULight-4E-BP1 as substrate incubated for 1 hr by LANCE Ul...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiaxing University

Curated by ChEMBL
LigandPNGBDBM50563253(CHEMBL4750601)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end amino acids) using ULight-4E-BP1 as substrate incubated for 1 hr by LANCE Ul...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50563254(CHEMBL4757766)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human PI3Kalpha using PIP2 as substrate incubated for 1 hr by kinase-glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiaxing University

Curated by ChEMBL
LigandPNGBDBM50563254(CHEMBL4757766)
Affinity DataIC50: 141nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end amino acids) using ULight-4E-BP1 as substrate incubated for 1 hr by LANCE Ul...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed