Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50012692
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50559446(CHEMBL4779321)
Affinity DataIC50: 307nMAssay Description:Inhibition of VHL (unknown origin) assessed as phosphorylated peptide substrate incubated for 60 mins by TR-FRET based biochemical assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50559446(CHEMBL4779321)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of recombinant human GST-tagged ERK5 (1 to 398 assessed as phosphorylated peptide substrate incubated for 60 mins by TR-FRET based biochem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50559446(CHEMBL4779321)
Affinity DataIC50: 4.31E+3nMAssay Description:Inhibition of NanoLuc-tagged VHL in HEK293 cells incubated for 2 hrs by NanoBRET live cell assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed