Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 50013453
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566013(CHEMBL4800218)
Affinity DataKi:  0.610nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr in presence of 250 uM phenytoin liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566011(CHEMBL4790607)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566027(CHEMBL4795418)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566012(CHEMBL4799971)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50396352(CHEMBL2170062)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566012(CHEMBL4799971)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr in presence of 250 uM phenytoin liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566005(CHEMBL4777990)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50001028(Talwin | PENTAZOCINE (+) | Pentazocine,(+/-) | 6,1...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566026(CHEMBL4799774)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566010(CHEMBL4780832)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566012(CHEMBL4799971)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566014(CHEMBL4796342)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566009(CHEMBL4793144)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr in presence of 250 uM phenytoin liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566008(CHEMBL4784828)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566028(CHEMBL4796616)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50396352(CHEMBL2170062)
Affinity DataKi:  17nMAssay Description:Binding affinity to human sigma-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566009(CHEMBL4793144)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566025(CHEMBL4798543)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566017(CHEMBL4785662)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566015(CHEMBL4780883)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50396352(CHEMBL2170062)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566019(CHEMBL4798816)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566020(CHEMBL4778313)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566021(CHEMBL4776769)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566023(CHEMBL4797095)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566009(CHEMBL4793144)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566006(CHEMBL4787318)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566022(CHEMBL4790480)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566016(CHEMBL4800355)
Affinity DataKi:  82nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566024(CHEMBL4778319)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566018(CHEMBL4799270)
Affinity DataKi:  96nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566007(CHEMBL4793067)
Affinity DataKi:  131nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566028(CHEMBL4796616)
Affinity DataKi:  750nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566022(CHEMBL4790480)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50396352(CHEMBL2170062)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566012(CHEMBL4799971)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566014(CHEMBL4796342)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566015(CHEMBL4780883)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566035(CHEMBL4789485)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566034(CHEMBL4793045)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566023(CHEMBL4797095)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566016(CHEMBL4800355)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566033(CHEMBL4783895)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50566032(CHEMBL4776817)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
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