Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50012364
TargetSodium/bile acid cotransporter(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM50556959(CHEMBL4781848)
Affinity DataIC50: 66nMAssay Description:Inhibition of human NTCP-mediated [3H]-TCA uptake expressed in human HepG2 cells incubated for 2 hrs followed by substrate addition and measured for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 750nMAssay Description:Inhibition of OATP1B1 (unknown origin) mediated [3H]-estrone sulfate uptake expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM50556959(CHEMBL4781848)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of OATP1B1 (unknown origin) mediated [3H]-estrone sulfate uptake expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed