Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50012962
TargetMitogen-activated protein kinase 10(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM86632(JNK-IN-7)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of wild-type human partial length JNK3 (V28 to Q422 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM86632(JNK-IN-7)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of wild-type human full length JNK1 (M1 to Q384 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM86632(JNK-IN-7)
Affinity DataIC50: 2nMAssay Description:Inhibition of wild-type human full length JNK2 (M1 to Q382 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50373415(CHEMBL256713)
Affinity DataIC50: 9nMAssay Description:Inhibition of wild-type human partial length IRAK1 (R194 to S712 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561821(CHEMBL4782804)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant IRAK1 (unknown origin) by Invitrogen adapta assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM86632(JNK-IN-7)
Affinity DataIC50: 14nMAssay Description:Inhibition of wild-type human partial length IRAK1 (R194 to S712 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50373415(CHEMBL256713)
Affinity DataIC50: 17nMAssay Description:Inhibition of wild-type human partial length IRAK4 (M1 to S460 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561824(CHEMBL4784448)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant IRAK1 (unknown origin) by Invitrogen adapta assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561822(CHEMBL4799481)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant IRAK1 (unknown origin) by Invitrogen adapta assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561826(CHEMBL4790193)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant IRAK1 (unknown origin) by Invitrogen adapta assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561823(CHEMBL4786242)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant IRAK1 (unknown origin) by Invitrogen adapta assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 19(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561821(CHEMBL4782804)
Affinity DataIC50: 57nMAssay Description:Inhibition of wild-type human partial length YSK4 (T1019 to H1328 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561827(CHEMBL4751092)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant IRAK1 (unknown origin) by Invitrogen adapta assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561825(CHEMBL4781702)
Affinity DataIC50: 259nMAssay Description:Inhibition of recombinant IRAK1 (unknown origin) by Invitrogen adapta assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561821(CHEMBL4782804)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRAK4 (unknown origin) using methylcoumarin-labeled peptide as substrate in presence of ATP by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561826(CHEMBL4790193)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRAK4 (unknown origin) using methylcoumarin-labeled peptide as substrate in presence of ATP by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM86632(JNK-IN-7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild-type human partial length IRAK4 (M1 to S460 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561825(CHEMBL4781702)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRAK4 (unknown origin) using methylcoumarin-labeled peptide as substrate in presence of ATP by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561824(CHEMBL4784448)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRAK4 (unknown origin) using methylcoumarin-labeled peptide as substrate in presence of ATP by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561823(CHEMBL4786242)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRAK4 (unknown origin) using methylcoumarin-labeled peptide as substrate in presence of ATP by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561822(CHEMBL4799481)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRAK4 (unknown origin) using methylcoumarin-labeled peptide as substrate in presence of ATP by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed