Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50012954
TargetTyrosine-protein kinase JAK3(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 236nMAssay Description:Inhibition of JAK3 in mouse BaF3 cells assessed as reduction in cell viability by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50561795(CHEMBL4776512)
Affinity DataIC50: 564nMAssay Description:Inhibition of JAK3 in mouse BaF3 cells assessed as reduction in cell viability in presence of 0.1 mM H2O2 by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataIC50: 764nMAssay Description:Inhibition of JAK3 in mouse BaF3 cells assessed as reduction in cell viability by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataIC50: 790nMAssay Description:Inhibition of JAK3 in mouse BaF3 cells assessed as reduction in cell viability in presence of 0.1 mM H2O2 by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50561795(CHEMBL4776512)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 in mouse BaF3 cells assessed as reduction in cell viability by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed