Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50012127
TargetProstaglandin G/H synthase 1(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554356(CHEMBL4758733)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide dye based ag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554356(CHEMBL4758733)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant wild-type human topoisomerase 2alpha expressed in Saccharomyces cerevisiae using supercoiled pBR322 DNA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554356(CHEMBL4758733)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide dye based ag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554350(CHEMBL3548140)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide dye based ag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554351(CHEMBL4753427)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide dye based ag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554352(CHEMBL4784903)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide dye based ag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554355(CHEMBL4782390)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide dye based ag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554353(CHEMBL4749636)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide dye based ag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-beta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554356(CHEMBL4758733)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant wild-type human topoisomerase 2beta expressed in Saccharomyces cerevisiae using supercoiled pBR322 DNA as substrate measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50554354(CHEMBL4750336)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of recombinant human topoisomerase 2alpha using supercoiled pBR322 DNA as substrate incubated for 60 mins by ethidium bromide dye based ag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed