Compile Data Set for Download or QSAR
Report error Found 82 Enz. Inhib. hit(s) with all data for entry = 50012090
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554035(CHEMBL4790231)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554052(CHEMBL4763667)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554050(CHEMBL4752248)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554057(CHEMBL4740830)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554056(CHEMBL4782307)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554054(CHEMBL4751166)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554051(CHEMBL4795827)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357630(US10214527, Example 2 | 7-(3- chlorobenzyl)- 3H- [...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357653(US10214527, Example 25 | 3-((5-amino- 3H- [1,2,3]t...)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554036(CHEMBL4764237)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554055(CHEMBL4755252)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357629(US10214527, Example 1 | 7-benzyl-3H-[1,2,3]triazol...)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357653(US10214527, Example 25 | 3-((5-amino- 3H- [1,2,3]t...)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554053(CHEMBL4776151)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554036(CHEMBL4764237)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetEosinophil peroxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357629(US10214527, Example 1 | 7-benzyl-3H-[1,2,3]triazol...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human EPX bromination activity using tyrosine as substrate by measuring 3-bromo tyrosine formation incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357630(US10214527, Example 2 | 7-(3- chlorobenzyl)- 3H- [...)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357651(US10214527, Example 23 | 7-(2- fluorobenzyl)- 3H- ...)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50507389(CHEMBL4530093)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357629(US10214527, Example 1 | 7-benzyl-3H-[1,2,3]triazol...)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357651(US10214527, Example 23 | 7-(2- fluorobenzyl)- 3H- ...)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50507389(CHEMBL4530093)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357634(US10214527, Example 6 | 7-(naphthalen- 2-ylmethyl)...)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554049(CHEMBL4760380)
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554045(CHEMBL4800005)
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357645(US10214527, Example 17)
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357629(US10214527, Example 1 | 7-benzyl-3H-[1,2,3]triazol...)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetEosinophil peroxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50: 92nMAssay Description:Inhibition of human EPX bromination activity using tyrosine as substrate by measuring 3-bromo tyrosine formation incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554048(CHEMBL4747086)
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50106515(7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-y...)
Affinity DataIC50: 103nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50106515(7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-y...)
Affinity DataIC50: 105nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554038(CHEMBL4762281)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554043(CHEMBL4763067)
Affinity DataIC50: 124nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357645(US10214527, Example 17)
Affinity DataIC50: 127nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554042(CHEMBL4761170)
Affinity DataIC50: 141nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554044(CHEMBL4792720)
Affinity DataIC50: 159nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357634(US10214527, Example 6 | 7-(naphthalen- 2-ylmethyl)...)
Affinity DataIC50: 188nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357633(US10214527, Example 5 | 7-(2- chlorobenzyl)- 3H- [...)
Affinity DataIC50: 286nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetEosinophil peroxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554035(CHEMBL4790231)
Affinity DataIC50: 360nMAssay Description:Inhibition of human EPX bromination activity using tyrosine as substrate by measuring 3-bromo tyrosine formation incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554038(CHEMBL4762281)
Affinity DataIC50: 428nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554047(CHEMBL4763260)
Affinity DataIC50: 616nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357654(US10214527, Example 26 | 7-(3- (trifluorometh- yl)...)
Affinity DataIC50: 683nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357633(US10214527, Example 5 | 7-(2- chlorobenzyl)- 3H- [...)
Affinity DataIC50: 990nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357654(US10214527, Example 26 | 7-(3- (trifluorometh- yl)...)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554046(CHEMBL4783713)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554037(CHEMBL4760627)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554043(CHEMBL4763067)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetThyroid peroxidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357629(US10214527, Example 1 | 7-benzyl-3H-[1,2,3]triazol...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of TPO (unknown origin) using 3-iodo tyrosine as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50554044(CHEMBL4792720)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
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