Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50012073
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CES1A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CES1A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553899(CHEMBL4756235)
Affinity DataIC50: 100nMAssay Description:Inhibition of CES1A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50310723(30-norhederagenin | CHEMBL1081326)
Affinity DataIC50: 100nMAssay Description:Inhibition of CES1A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553898(CHEMBL4789029)
Affinity DataIC50: 100nMAssay Description:Inhibition of CES1A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50242248(olean-12-en-3-one | beta-amyrenone | beta-amyrinon...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CES1A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50377927(Clerodol | Fagarasterol | Farganasterol | Monogyno...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CES1A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553897(CHEMBL4800408)
Affinity DataIC50: 100nMAssay Description:Inhibition of CES1A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM23209((1R,2R,5S,8R,9R,10R,13R,14R,17S,18R,19R)-17-hydrox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CES1A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553898(CHEMBL4789029)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553899(CHEMBL4756235)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50310723(30-norhederagenin | CHEMBL1081326)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553890(CHEMBL4756952)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50242248(olean-12-en-3-one | beta-amyrenone | beta-amyrinon...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50377927(Clerodol | Fagarasterol | Farganasterol | Monogyno...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553897(CHEMBL4800408)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM23209((1R,2R,5S,8R,9R,10R,13R,14R,17S,18R,19R)-17-hydrox...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553896(CHEMBL4796626)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553895(CHEMBL448219)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553894(CHEMBL4763754)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553893(CHEMBL4759191)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553892(CHEMBL4798331)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50553891(CHEMBL4763518)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed