Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50011050
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50540048(CHEMBL4636092)
Affinity DataEC50:  3.80E+4nMAssay Description:Activation of SIRT6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataEC50:  5.35E+3nMAssay Description:Activation of N-terminal his-tagged human SIRT6 expressed in Escherichia coli M15 [pREP4] assessed as increase in peptide demyristoylation incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataEC50:  8.91E+3nMAssay Description:Activation of N-terminal his-tagged human SIRT6 expressed in Escherichia coli M15 [pREP4] assessed as increase in deacetylation activity incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataEC50:  5.49E+3nMAssay Description:Activation of N-terminal his-tagged human SIRT6 expressed in Escherichia coli M15 [pREP4] assessed as increase in deacetylation activity incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataKd:  8.85E+3nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT6 expressed in Escherichia coli M15 [pREP4] by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataKd:  5.52E+3nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT6 expressed in Escherichia coli M15 [pREP4] by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528218(CHEMBL4551664)
Affinity DataKd:  9.51E+3nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT6 expressed in Escherichia coli M15 [pREP4] by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528218(CHEMBL4551664)
Affinity DataEC50:  1.03E+4nMAssay Description:Allosteric activation of SIRT6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 1.71E+5nMAssay Description:Inhibition of SIRT1 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HDAC11 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HDAC10 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HDAC9 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HDAC8 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HDAC7 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HDAC6 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HDAC5 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HDAC4 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HDAC3 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HDAC2 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT5 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT3 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50544391(CHEMBL4636189)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT2 (unknown origin) by FDL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed