Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50012254
TargetDNA repair endonuclease XPF(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(cid_421105 | 4-[(6-chloro-2-methoxy-9-acridinyl)am...)
Affinity DataKd:  140nMAssay Description:Binding affinity to His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells by steady-state fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA repair endonuclease XPF(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50555906(CHEMBL4759590)
Affinity DataKd:  85nMAssay Description:Binding affinity to His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells by steady-state fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA repair endonuclease XPF(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50555906(CHEMBL4759590)
Affinity DataIC50: 490nMAssay Description:Inhibition of human His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells using 6-FAM-5'CAGCGCTCGG(20T)CCGAGCGCTG-3'-dabcyl measu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA repair endonuclease XPF(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(cid_421105 | 4-[(6-chloro-2-methoxy-9-acridinyl)am...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of human His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells using 6-FAM-5'CAGCGCTCGG(20T)CCGAGCGCTG-3'-dabcyl measu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed