Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50012242
TargetMetabotropic glutamate receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50555839(CHEMBL4793451)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human mGlu2 receptor expressed in CHO cell membranes by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataEC50:  76nMAssay Description:Agonist activity at human mGlu3 receptor expressed in CHO cell membranes by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50555839(CHEMBL4793451)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human mGlu3 receptor expressed in CHO cell membranes by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataEC50:  154nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in CHO cell membranes by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataEC50:  97nMAssay Description:Agonist activity at rat mGlu3 receptor expressed in CHO cell membranes by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50555839(CHEMBL4793451)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human mGlu3 receptor expressed in CHO cell membranes by GTPgammaS binding assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataEC50:  153nMAssay Description:Agonist activity at human mGlu2 receptor expressed in CHO cell membranes by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human mGlu4 receptor expressed in CHO cell membranes by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human mGlu1 receptor expressed in CHO cell membranes by intracellular Ca2+ assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human mGlu6 receptor expressed in HEK293T cell membranes by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human mGlu8 receptor expressed in CHO cell membranes by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human mGlu8 receptor expressed in CHO cell membranes in presence of glutamate by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human mGlu6 receptor expressed in HEK293T cell membranes in presence of glutamate by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human mGlu4 receptor expressed in CHO cell membranes in presence of glutamate by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human mGlu1 receptor expressed in CHO cell membranes in presence of glutamate by intracellular Ca2+ assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human mGlu3 receptor expressed in CHO cell membranes in presence of glutamate by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50094841(2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarbox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human mGlu2 receptor expressed in CHO cell membranes in presence of glutamate by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed