Compile Data Set for Download or QSAR
Report error Found 110 Enz. Inhib. hit(s) with all data for entry = 50011029
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544133(CHEMBL4636148)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 Hunter cell incubated for 30 to 60 mins by hit-hunter cAMP assay based chemil...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544139(CHEMBL4633786)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 Hunter cell incubated for 30 to 60 mins by hit-hunter cAMP assay based chemil...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 Hunter cell incubated for 30 to 60 mins by hit-hunter cAMP assay based chemil...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544133(CHEMBL4636148)
Affinity DataIC50: 125nMAssay Description:Antagonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 Hunter cell preincubated for 30 mins followed by incubation with agonist f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544139(CHEMBL4633786)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 Hunter cell preincubated for 30 mins followed by incubation with agonist f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataIC50: 310nMAssay Description:Antagonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 Hunter cell preincubated for 30 mins followed by incubation with agonist f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM21393(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKi:  0.860nMAssay Description:Displacement of [3H]-N-Methylspiperone from human dopamine D4 receptor expressed in stable HEK cells incubated for 90 mins by microbeta counting meth...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50087033((1R,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexah...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-LSD from human 5-HT7 receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50487259(CHEBI:64219 | [3H]NEMONAPRIDE)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-N-Methylspiperone from dopamine D3 receptor (unknown origin) incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-Ketanserin from 5-HT2A receptor (unknown origin) incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50098549((6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]-LSD from human 5-HT7 receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50008735(CHEMBL8514 | BUTACLAMOL,d- | (+)-3-(tert-butyl)-(3...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]-SCH23390 from human dopamine D1 receptor expressed in HEKT cells incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544133(CHEMBL4636148)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]-N-Methylspiperone from human dopamine D2 receptor expressed in stable fibroblast cells incubated for 90 mins by microbeta counti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544139(CHEMBL4633786)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544140(CHEMBL4633042)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544137(CHEMBL4641502)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544130(CHEMBL4635676)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50090078(CHEMBL3581245)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-LSD from human 5-HT7 receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50087033((1R,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexah...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544135(CHEMBL4636329)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544129(CHEMBL4637084)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544132(CHEMBL4643640)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544139(CHEMBL4633786)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544131(CHEMBL4647589)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544128(CHEMBL4649646)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544123(CHEMBL4632872)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544122(CHEMBL4644833)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544133(CHEMBL4636148)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544128(CHEMBL4649646)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544116(CHEMBL4649697)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544126(CHEMBL4645997)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544143(CHEMBL4640588)
Affinity DataKi:  86nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544143(CHEMBL4640588)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544138(CHEMBL4649078)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544142(CHEMBL4646172)
Affinity DataKi:  102nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544141(CHEMBL4639400)
Affinity DataKi:  104nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544141(CHEMBL4639400)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]-Ketanserin from 5-HT2A receptor (unknown origin) incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544121(CHEMBL4640281)
Affinity DataKi:  114nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544125(CHEMBL4640332)
Affinity DataKi:  123nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544126(CHEMBL4645997)
Affinity DataKi:  127nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544141(CHEMBL4639400)
Affinity DataKi:  132nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544140(CHEMBL4633042)
Affinity DataKi:  132nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544131(CHEMBL4647589)
Affinity DataKi:  133nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50098549((6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...)
Affinity DataKi:  142nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50544138(CHEMBL4649078)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]-LSD from human 5-HT7A receptor expresssed in stable HEK cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50090078(CHEMBL3581245)
Affinity DataKi:  153nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expresssed in stable CHO cell membrane incubated for 90 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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