Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50012757
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559980(CHEMBL4763502)
Affinity DataEC50:  830nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559973(CHEMBL4790858)
Affinity DataEC50:  40nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559974(CHEMBL4790850)
Affinity DataEC50:  10nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559975(CHEMBL4753374)
Affinity DataEC50:  220nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559976(CHEMBL4785159)
Affinity DataEC50:  250nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559977(CHEMBL4777918)
Affinity DataEC50:  280nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559978(CHEMBL4745690)
Affinity DataEC50:  330nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559979(CHEMBL4798704)
Affinity DataEC50:  700nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559981(CHEMBL4791250)
Affinity DataEC50:  5.05E+3nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559982(CHEMBL4747542)
Affinity DataEC50:  6.80E+3nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559983(CHEMBL4800568)
Affinity DataEC50:  230nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559984(CHEMBL4788014)
Affinity DataEC50:  500nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559985(CHEMBL4799568)
Affinity DataEC50:  500nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559986(CHEMBL4749840)
Affinity DataEC50:  630nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559963(CHEMBL4788965)
Affinity DataIC50: 900nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559964(CHEMBL4757017)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036632(CHEMBL3354284)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036610(CHEMBL3354264)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036612(CHEMBL3354266)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559965(CHEMBL4790126)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036611(CHEMBL3354265)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036629(CHEBI:66876 | Avanafil | Stendra | TA-1790)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036629(CHEBI:66876 | Avanafil | Stendra | TA-1790)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036616(CHEMBL3354270)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559966(CHEMBL4749671)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559967(CHEMBL4741817)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036631(CHEMBL3352836)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559968(CHEMBL4790060)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036618(CHEMBL3354272)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036617(CHEMBL3354271)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036615(CHEMBL3354269)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559971(CHEMBL4747008)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036620(CHEMBL3354274)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559969(CHEMBL4781808)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50036622(CHEMBL3354276)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559970(CHEMBL4798650)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50559972(CHEMBL4748431)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed