Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50010757
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541816(CHEMBL4633304)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of DGKA/DGKZ in human CD8 cells assessed as induction of CD8 activation by measuring IFNgamma level after 20 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541814(CHEMBL4648848)
Affinity DataIC50: 26nMAssay Description:Inhibition of DGKA/DGKZ in human CD8 cells assessed as induction of CD8 activation by measuring IFNgamma level after 20 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541812(CHEMBL4647083)
Affinity DataIC50: 28nMAssay Description:Inhibition of DGKA/DGKZ in human CD8 cells assessed as induction of CD8 activation by measuring IFNgamma level after 20 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541815(CHEMBL4646970)
Affinity DataIC50: 39nMAssay Description:Inhibition of DGKA/DGKZ in human CD8 cells assessed as induction of CD8 activation by measuring IFNgamma level after 20 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha/zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541810(CHEMBL4645744)
Affinity DataIC50: 43nMAssay Description:Inhibition of DGKA/DGKZ in human CD8 cells assessed as induction of CD8 activation by measuring IFNgamma level after 20 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541810(CHEMBL4645744)
Affinity DataIC50: 190nMAssay Description:Inhibition of full-length C-terminal His6 tagged TVMV-pFBgate fused human DGKalpha expressed in baculovirus infected Sf9 insect cells using liposome ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541813(CHEMBL4646998)
Affinity DataIC50: 190nMAssay Description:Inhibition of DGKA/DGKZ in human CD8 cells assessed as induction of CD8 activation by measuring IFNgamma level after 20 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541814(CHEMBL4648848)
Affinity DataIC50: 330nMAssay Description:Inhibition of full length C-terminal His6tagged TVMV-His-pFBgate fused human DGK-zeta expressed in baculovirus infected Sf9 insect cells using liposo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541810(CHEMBL4645744)
Affinity DataIC50: 400nMAssay Description:Inhibition of full length C-terminal His6tagged TVMV-His-pFBgate fused human DGK-zeta expressed in baculovirus infected Sf9 insect cells using liposo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541810(CHEMBL4645744)
Affinity DataIC50: 460nMAssay Description:Inhibition of DGKalpha/zeta in human whole blood assessed as induction of T-cell activation by measuring IFNgamma level preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541816(CHEMBL4633304)
Affinity DataIC50: 490nMAssay Description:Inhibition of full length C-terminal His6tagged TVMV-His-pFBgate fused human DGK-zeta expressed in baculovirus infected Sf9 insect cells using liposo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541814(CHEMBL4648848)
Affinity DataIC50: 580nMAssay Description:Inhibition of full-length C-terminal His6 tagged TVMV-pFBgate fused human DGKalpha expressed in baculovirus infected Sf9 insect cells using liposome ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541816(CHEMBL4633304)
Affinity DataIC50: 600nMAssay Description:Inhibition of DGKalpha/zeta in human whole blood assessed as induction of T-cell activation by measuring IFNgamma level preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541814(CHEMBL4648848)
Affinity DataIC50: 680nMAssay Description:Inhibition of DGKalpha/zeta in human whole blood assessed as induction of T-cell activation by measuring IFNgamma level preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541812(CHEMBL4647083)
Affinity DataIC50: 730nMAssay Description:Inhibition of DGKalpha/zeta in human whole blood assessed as induction of T-cell activation by measuring IFNgamma level preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541812(CHEMBL4647083)
Affinity DataIC50: 770nMAssay Description:Inhibition of full-length C-terminal His6 tagged TVMV-pFBgate fused human DGKalpha expressed in baculovirus infected Sf9 insect cells using liposome ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541812(CHEMBL4647083)
Affinity DataIC50: 830nMAssay Description:Inhibition of full length C-terminal His6tagged TVMV-His-pFBgate fused human DGK-zeta expressed in baculovirus infected Sf9 insect cells using liposo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541815(CHEMBL4646970)
Affinity DataIC50: 940nMAssay Description:Inhibition of DGKalpha/zeta in human whole blood assessed as induction of T-cell activation by measuring IFNgamma level preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541811(CHEMBL4637336)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of DGKA/DGKZ in human CD8 cells assessed as induction of CD8 activation by measuring IFNgamma level after 20 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541816(CHEMBL4633304)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of full-length C-terminal His6 tagged TVMV-pFBgate fused human DGKalpha expressed in baculovirus infected Sf9 insect cells using liposome ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541815(CHEMBL4646970)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of full-length C-terminal His6 tagged TVMV-pFBgate fused human DGKalpha expressed in baculovirus infected Sf9 insect cells using liposome ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541811(CHEMBL4637336)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of full length C-terminal His6tagged TVMV-His-pFBgate fused human DGK-zeta expressed in baculovirus infected Sf9 insect cells using liposo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541811(CHEMBL4637336)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of full-length C-terminal His6 tagged TVMV-pFBgate fused human DGKalpha expressed in baculovirus infected Sf9 insect cells using liposome ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541815(CHEMBL4646970)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of full length C-terminal His6tagged TVMV-His-pFBgate fused human DGK-zeta expressed in baculovirus infected Sf9 insect cells using liposo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541811(CHEMBL4637336)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of DGKalpha/zeta in human whole blood assessed as induction of T-cell activation by measuring IFNgamma level preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541813(CHEMBL4646998)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of full length C-terminal His6tagged TVMV-His-pFBgate fused human DGK-zeta expressed in baculovirus infected Sf9 insect cells using liposo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase zeta(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541813(CHEMBL4646998)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of DGKalpha/zeta in human whole blood assessed as induction of T-cell activation by measuring IFNgamma level preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50541813(CHEMBL4646998)
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of full-length C-terminal His6 tagged TVMV-pFBgate fused human DGKalpha expressed in baculovirus infected Sf9 insect cells using liposome ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed