Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50012748
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM468322(US10806720, Compound 1002 | US11648234, Compound 1...)
Affinity DataIC50: 2.00E+3nMAssay Description:SARD activity at AR-LBD T877A mutant (unknown origin) after 4 hrs by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM468322(US10806720, Compound 1002 | US11648234, Compound 1...)
Affinity DataIC50: 2.00E+3nMAssay Description:SARD activity at AR-LBD F876L mutant (unknown origin) after 4 hrs by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50559923(CHEMBL4758041)
Affinity DataIC50: 6.00E+3nMAssay Description:Antagonist activity at recombinant GST/His-tagged rat androgen receptor amino-terminal domain by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50529667(CHEMBL4444904 | US10806720, Compound 11 | US112305...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-mibolerone from GST-tagged human AR-LBD expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50529647(CHEMBL4584527 | US10806720, Compound 17 | US112305...)
Affinity DataKi:  267nMAssay Description:Displacement of [3H]-mibolerone from GST-tagged human AR-LBD expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataKi:  3.64E+3nMAssay Description:Displacement of [3H]-mibolerone from GST-tagged human AR-LBD expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed