Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50010986
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543951(CHEMBL4639181)
Affinity DataIC50: 5nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543941(CHEMBL4648874)
Affinity DataIC50: 5nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543942(CHEMBL4633328)
Affinity DataIC50: 5nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543950(CHEMBL4642170)
Affinity DataIC50: 5nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543945(CHEMBL4648058)
Affinity DataIC50: 5nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543948(CHEMBL4644928)
Affinity DataIC50: 5nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM150300(US8987247, 1)
Affinity DataIC50: 10nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543946(CHEMBL4640364)
Affinity DataIC50: 10nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543935(CHEMBL1615314)
Affinity DataIC50: 10nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543956(CHEMBL4635086)
Affinity DataIC50: 12nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543949(CHEMBL4642254)
Affinity DataIC50: 14nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543936(CHEMBL4644927)
Affinity DataIC50: 15nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543937(CHEMBL4642850)
Affinity DataIC50: 20nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543954(CHEMBL4632441)
Affinity DataIC50: 21nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543952(CHEMBL4649619)
Affinity DataIC50: 24nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543957(CHEMBL4634718)
Affinity DataIC50: 28nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543944(CHEMBL4641024)
Affinity DataIC50: 32nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543943(CHEMBL4644240)
Affinity DataIC50: 45nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543947(CHEMBL4636259)
Affinity DataIC50: 53nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543938(CHEMBL4637973)
Affinity DataIC50: 97nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543940(CHEMBL4637347)
Affinity DataIC50: 119nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543953(CHEMBL4639861)
Affinity DataIC50: 559nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543939(CHEMBL4644784)
Affinity DataIC50: 979nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50543955(CHEMBL4636893)
Affinity DataIC50: 1.66E+3nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM150300(US8987247, 1)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of FAAH (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM150300(US8987247, 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to CB1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM150300(US8987247, 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed