Compile Data Set for Download or QSAR
Report error Found 59 Enz. Inhib. hit(s) with all data for entry = 50004011
TargetSigma non-opioid intracellular receptor 1(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50251208(CHEMBL4088272)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-pentazocin from the Sigma1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50048866(1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronap...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-pentazocin from the Sigma1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma intracellular receptor 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50048866(1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronap...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-DTG from the Sigma2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50253157((2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-pentazocin from the Sigma1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50253157((2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]...)
Affinity DataKi:  20nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M1 (CHRM1) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma intracellular receptor 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50253157((2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-DTG from the Sigma2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50253157((2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]...)
Affinity DataKi:  28nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M5 (CHRM5) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50253157((2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]...)
Affinity DataKi:  54nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M4 (CHRM4) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50253157((2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]...)
Affinity DataKi:  56nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M3 (CHRM3) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]-pentazocin from the Sigma1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma intracellular receptor 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM24226(cid_2247 | [3H]-ASTEMIZOLE | Hismanal | ASTEMIZOLE...)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]-DTG from the Sigma2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma intracellular receptor 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM24226(cid_2247 | [3H]-ASTEMIZOLE | Hismanal | ASTEMIZOLE...)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]-DTG from the Sigma2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50253157((2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]...)
Affinity DataKi:  117nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M2 (CHRM2) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50467780(CHEBI:5801 | Hydroxychloroquine | med.21724, Compo...)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]-pentazocin from the Sigma1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50253157((2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]...)
Affinity DataKi:  158nMAssay Description:hERG binding assays: Displacement of [3H]-Dofetilide (5 nM final) from hERG membranes obtained from HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50253157((2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]...)
Affinity DataKi:  170nMAssay Description:Activity of compound against Alpha-2A (ADRA2A) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50253157((2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]...)
Affinity DataKi:  224nMAssay Description:Activity of compound against Alpha 2C (ADRA2C) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50253157((2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]...)
Affinity DataKi:  479nMAssay Description:Activity of compound against Alpha 2B (ADRA2B) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50048866(1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronap...)
Affinity DataKi:  479nMAssay Description:Activity of compound against Alpha 2C (ADRA2C) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma intracellular receptor 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataKi:  501nMAssay Description:Displacement of [3H]-DTG from the Sigma2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma intracellular receptor 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50251208(CHEMBL4088272)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]-DTG from the Sigma2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma intracellular receptor 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50467780(CHEBI:5801 | Hydroxychloroquine | med.21724, Compo...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-DTG from the Sigma2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50048866(1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronap...)
Affinity DataKi:  1.00E+3nMAssay Description:hERG binding assays: Displacement of [3H]-Dofetilide (5 nM final) from hERG membranes obtained from HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM24226(cid_2247 | [3H]-ASTEMIZOLE | Hismanal | ASTEMIZOLE...)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H]-pentazocin from the Sigma1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM24226(cid_2247 | [3H]-ASTEMIZOLE | Hismanal | ASTEMIZOLE...)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [3H]-pentazocin from the Sigma1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50048866(1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronap...)
Affinity DataKi:  1.51E+3nMAssay Description:Activity of compound against Alpha-2A (ADRA2A) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50467780(CHEBI:5801 | Hydroxychloroquine | med.21724, Compo...)
Affinity DataKi:  2.51E+3nMAssay Description:hERG binding assays: Displacement of [3H]-Dofetilide (5 nM final) from hERG membranes obtained from HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataKi:  3.16E+3nMAssay Description:hERG binding assays: Displacement of [3H]-Dofetilide (5 nM final) from hERG membranes obtained from HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataKi:  3.31E+3nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M3 (CHRM3) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50048866(1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronap...)
Affinity DataKi:  3.55E+3nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M5 (CHRM5) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50048866(1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronap...)
Affinity DataKi:  3.98E+3nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M4 (CHRM4) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataKi:  4.37E+3nMAssay Description:Activity of compound against Alpha-2A (ADRA2A) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataKi:  4.68E+3nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M2 (CHRM2) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50467780(CHEBI:5801 | Hydroxychloroquine | med.21724, Compo...)
Affinity DataKi:  4.79E+3nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M3 (CHRM3) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50048866(1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronap...)
Affinity DataKi:  4.79E+3nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M2 (CHRM2) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50467780(CHEBI:5801 | Hydroxychloroquine | med.21724, Compo...)
Affinity DataKi:  5.13E+3nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M2 (CHRM2) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50467780(CHEBI:5801 | Hydroxychloroquine | med.21724, Compo...)
Affinity DataKi:  5.50E+3nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M4 (CHRM4) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataKi:  5.75E+3nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M4 (CHRM4) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50467780(CHEBI:5801 | Hydroxychloroquine | med.21724, Compo...)
Affinity DataKi:  6.46E+3nMAssay Description:Activity of compound against Alpha-2A (ADRA2A) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50251208(CHEMBL4088272)
Affinity DataKi:  8.32E+3nMAssay Description:Activity of compound against Alpha-2A (ADRA2A) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataKi:  9.12E+3nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M1 (CHRM1) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50048866(1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronap...)
Affinity DataKi:  9.33E+3nMAssay Description:Activity of compound against Alpha 2B (ADRA2B) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50251208(CHEMBL4088272)
Affinity DataKi:  1.00E+4nMAssay Description:hERG binding assays: Displacement of [3H]-Dofetilide (5 nM final) from hERG membranes obtained from HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataKi:  1.00E+4nMAssay Description:Activity of compound against Alpha 2C (ADRA2C) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50251208(CHEMBL4088272)
Affinity DataKi:  1.00E+4nMAssay Description:Activity of compound against Alpha 2C (ADRA2C) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50467780(CHEBI:5801 | Hydroxychloroquine | med.21724, Compo...)
Affinity DataKi:  1.55E+4nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M1 (CHRM1) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50467780(CHEBI:5801 | Hydroxychloroquine | med.21724, Compo...)
Affinity DataKi:  1.58E+4nMAssay Description:Activity of compound against Alpha 2C (ADRA2C) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50048866(1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronap...)
Affinity DataKi:  1.95E+4nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M3 (CHRM3) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50467780(CHEBI:5801 | Hydroxychloroquine | med.21724, Compo...)
Affinity DataKi:  2.00E+4nMAssay Description:Activity of compound against Muscarinic acetylcholine receptor M5 (CHRM5) by displacement of 3H-QNBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Qbi Covid-19 Research Group (Qcrg)

Curated by ChEMBL
LigandPNGBDBM50251208(CHEMBL4088272)
Affinity DataKi:  2.04E+4nMAssay Description:Activity of compound against Alpha 2B (ADRA2B) adrenergic receptor by displacement of [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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