Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50018731
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of FTO (unknown origin) mediated m6A methylation by HPLC analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of full length human FTO expressed in Escherichia coli BL21(DE3) rosetta by HPLC analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of FTO (unknown origin) mediated m6A methylation by HPLC analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.95E+3nMAssay Description:Inhibition of FTO (unknown origin) (31 to 505 residues) mediated demethylation activity expressed in Escherichia coli BL21(DE3) using 15-mer ssRNA ol...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of FTO (unknown origin) (31 to 505 residues) by LC/MS analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.74E+4nMAssay Description:Displacement of dm6A-containing ssDNA from truncated N-terminal his-tagged human FTO (31 residues) mediated demethylation activity expressed in Esche...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Displacement of ssDNA from FTO (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.92E+4nMAssay Description:Inhibition of FTO (unknown origin) (31 to 505 residues) mediated demethylation activity expressed in Escherichia coli BL21(DE3) using 15-mer ssRNA ol...More data for this Ligand-Target Pair
