Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50011861
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 7.00E+5nMAssay Description:Positive allosteric modulation of GABAA alpha1beta3gamma2L in HEK cell plasma membrane assessed as increase in [3H]muscimol binding measured after 10...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 4.00E+4nMAssay Description:Positive allosteric modulation of GABAA alpha1beta3gamma2L in HEK cell plasma membrane assessed as increase in [3H]muscimol binding measured after 10...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 7.40E+3nMAssay Description:Positive allosteric modulation of GABAA alpha1beta3gamma2L in HEK cell plasma membrane assessed as increase in [3H]muscimol binding measured after 10...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 5.40E+3nMAssay Description:Positive allosteric modulation of GABAA alpha1beta3gamma2L in HEK cell plasma membrane assessed as increase in [3H]muscimol binding measured after 10...More data for this Ligand-Target Pair
3D Structure (crystal)TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 2.90E+3nMAssay Description:Positive allosteric modulation of GABAA alpha1beta3 in HEK cell plasma membrane assessed as increase in [3H]muscimol binding measured after 10 mins b...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 1.10E+4nMAssay Description:Positive allosteric modulation of GABAA alpha1beta3gamma2L in HEK cell plasma membrane assessed as increase in [3H]flunitrazepam binding measured aft...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: 1.00E+4nMAssay Description:Positive allosteric modulation of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GABA-induced ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataEC50: >5.00E+7nMAssay Description:Positive allosteric modulation of GABAA alpha1beta3gamma2L in HEK cell plasma membrane assessed as increase in [3H]muscimol binding measured after 10...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of [3H]pTFD-di-iPr-BnOH labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of [3H]azietomidate labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in ph...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of [3H]pTFD-di-iPr-BnOH labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of [3H]R-mTFD-MPAB labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in pho...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of [3H]pTFD-di-iPr-BnOH labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of [3H]R-mTFD-MPAB labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in pho...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 9.20E+4nMAssay Description:Inhibition of [3H]azietomidate labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in ph...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 2.43E+5nMAssay Description:Inhibition of [3H]R-mTFD-MPAB labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in pho...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 3.05E+5nMAssay Description:Inhibition of [3H]azietomidate labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in ph...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 4.60E+5nMAssay Description:Inhibition of [3H]azietomidate labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in ph...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 4.65E+5nMAssay Description:Inhibition of [3H]R-mTFD-MPAB labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in pho...More data for this Ligand-Target Pair
