Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50011847
TargetEphrin type-A receptor 7(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  3.26E+3nMAssay Description:Inhibition of human EPHA7 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
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PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  3.86E+3nMAssay Description:Inhibition of human NTRK1 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
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PubMed
TargetCyclin-dependent kinase 16(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  1.77E+3nMAssay Description:Inhibition of human CDK16 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
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PubMed
TargetDiscoidin domain-containing receptor 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  2.49E+3nMAssay Description:Inhibition of human DDR2 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
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PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  3.26E+3nMAssay Description:Inhibition of human ZAK incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
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PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  3.86E+3nMAssay Description:Inhibition of human MAP4K4 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  1.77E+3nMAssay Description:Inhibition of human FLT3 incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
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PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataEC50:  2.49E+3nMAssay Description:Inhibition of human RET incubated for 30 mins by Kinobead based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataKd:  340nMAssay Description:Binding affinity to human partial length FLT3 ITD/F691L double mutant expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
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PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataKd:  115nMAssay Description:Binding affinity to human partial length FLT3 ITD/F691L double mutant expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
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PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551643(CHEMBL4790597)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551643(CHEMBL4790597)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551649(CHEMBL4765060)
Affinity DataIC50: 3nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551649(CHEMBL4765060)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551644(CHEMBL4745937)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551647(CHEMBL4755980)
Affinity DataIC50: 11nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551650(CHEMBL4754982)
Affinity DataIC50: 12nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551650(CHEMBL4754982)
Affinity DataIC50: 28nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551648(CHEMBL4740264)
Affinity DataIC50: 34nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551646(CHEMBL4751666)
Affinity DataIC50: 85nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551645(CHEMBL4764595)
Affinity DataIC50: 133nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataIC50: 137nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551647(CHEMBL4755980)
Affinity DataIC50: 240nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551646(CHEMBL4751666)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551648(CHEMBL4740264)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50551645(CHEMBL4764595)
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed