Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50007660
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511346(CHEMBL4454154)
Affinity DataIC50: 1.01E+3nMAssay Description:Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511342(CHEMBL4538474)
Affinity DataIC50: 1.02E+3nMAssay Description:Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50304360(benzene-1,2,3,4-tetrayl tetrakis(hydrogen phosphat...)
Affinity DataIC50: 2.78E+3nMAssay Description:Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetInositol polyphosphate-5-phosphatase A(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511342(CHEMBL4538474)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetType II inositol 1,4,5-trisphosphate 5-phosphatase(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511342(CHEMBL4538474)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged INPP5B (259 to 563 residues) expressed in Escherichia coli BL21 (DE3) incubated for 5 mins usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511343(CHEMBL4473747)
Affinity DataIC50: 7.02E+3nMAssay Description:Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511344(CHEMBL4453163)
Affinity DataIC50: 1.13E+4nMAssay Description:Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetInositol polyphosphate-5-phosphatase A(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511343(CHEMBL4473747)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511345(CHEMBL4566548)
Affinity DataIC50: 1.42E+4nMAssay Description:Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetInositol polyphosphate-5-phosphatase A(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511344(CHEMBL4453163)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetType II inositol 1,4,5-trisphosphate 5-phosphatase(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511345(CHEMBL4566548)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged INPP5B (259 to 563 residues) expressed in Escherichia coli BL21 (DE3) incubated for 5 mins usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511342(CHEMBL4538474)
Affinity DataIC50: 6.93E+4nMAssay Description:Displacement of Ins(1,3,4,5)P4 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetInositol polyphosphate-5-phosphatase A(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511346(CHEMBL4454154)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetInositol polyphosphate-5-phosphatase A(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511345(CHEMBL4566548)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetInositol polyphosphate-5-phosphatase A(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50304360(benzene-1,2,3,4-tetrayl tetrakis(hydrogen phosphat...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511342(CHEMBL4538474)
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of His-tagged SHIP2 (unknown origin) incubated for 5 mins using Ins(1,3,4,5)P4 as substrate by malachite green reagent based phosphate ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511345(CHEMBL4566548)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of Ins(1,3,4,5)P4 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed