Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50018469
TargetGlutathione S-transferase omega-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50458512(CHEMBL4215608)
Affinity DataIC50: 21nMAssay Description:Inhibition of SE-Rh binding to human recombinant GSTO1 preincubated with compound for 30 mins followed by SE-Rh addition and measured after 1 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetGlutathione S-transferase omega-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50458512(CHEMBL4215608)
Affinity DataIC50: 35nMAssay Description:Inhibition of SE-Rh binding to human recombinant GSTO1 in human MDA-MB-435 cells incubated for 1 hrs by SDS-PAGE based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50608552(CHEMBL5269107)
Affinity DataKi:  5.10nMAssay Description:Inhibition of human GBA2 over-expressed in HEK293T cells using 4-methylumbeliferone as substrate incubated for 1 hrs by FluoPol-ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50608553(CHEMBL5291161)
Affinity DataKi:  7.70nMAssay Description:Inhibition of human GBA2 over-expressed in HEK293T cells using 4-methylumbeliferone as substrate incubated for 1 hrs by FluoPol-ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed