Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50009518
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50108877(CHEMBL1324 | Tasmar | Ro-40-7592 | (3,4-dihydroxy-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529561(CHEMBL4462175)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529578(CHEMBL4461693)
Affinity DataIC50: 10nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529577(CHEMBL4470211)
Affinity DataIC50: 10nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529585(CHEMBL4458006)
Affinity DataIC50: 13nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529576(CHEMBL4531460)
Affinity DataIC50: 16nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529575(CHEMBL4449462)
Affinity DataIC50: 38nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529574(CHEMBL4447751)
Affinity DataIC50: 40nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529571(CHEMBL4453736)
Affinity DataIC50: 40nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529572(CHEMBL4583818)
Affinity DataIC50: 40nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529573(CHEMBL4523002)
Affinity DataIC50: 50nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529570(CHEMBL4476127)
Affinity DataIC50: 50nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529580(CHEMBL4556206)
Affinity DataIC50: 60nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529560(CHEMBL4577912)
Affinity DataIC50: 63nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529562(CHEMBL4587566)
Affinity DataIC50: 100nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529565(CHEMBL4438313)
Affinity DataIC50: 220nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529569(CHEMBL4538981)
Affinity DataIC50: 250nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529584(CHEMBL4518323)
Affinity DataIC50: 400nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529581(CHEMBL4442598)
Affinity DataIC50: 450nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529582(CHEMBL4551380)
Affinity DataIC50: 630nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529564(CHEMBL4446921)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529568(CHEMBL4566961)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529579(CHEMBL4454788)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529571(CHEMBL4453736)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged S-COMT expressed in 293-6E cells using 7,8-dihydroxy-4-methylcoumarin as substrate and SAM as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529561(CHEMBL4462175)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged S-COMT expressed in 293-6E cells using 7,8-dihydroxy-4-methylcoumarin as substrate and SAM as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529578(CHEMBL4461693)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged S-COMT expressed in 293-6E cells using 7,8-dihydroxy-4-methylcoumarin as substrate and SAM as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529576(CHEMBL4531460)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged S-COMT expressed in 293-6E cells using 7,8-dihydroxy-4-methylcoumarin as substrate and SAM as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529565(CHEMBL4438313)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged S-COMT expressed in 293-6E cells using 7,8-dihydroxy-4-methylcoumarin as substrate and SAM as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529566(CHEMBL4516338)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529578(CHEMBL4461693)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529571(CHEMBL4453736)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529578(CHEMBL4461693)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529583(CHEMBL4526054)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529567(CHEMBL4571097)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529563(CHEMBL4448560)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50529571(CHEMBL4453736)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed