Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50010574
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of North Carolina Greensboro

Curated by ChEMBL
LigandPNGBDBM50540270(CHEMBL4646089)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 (DE3) cells using PNPP as substate preincubated for 5 mins followed by substrate additon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of North Carolina Greensboro

Curated by ChEMBL
LigandPNGBDBM50540269(CHEMBL4647463)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 (DE3) cells using PNPP as substate preincubated for 5 mins followed by substrate additon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of North Carolina Greensboro

Curated by ChEMBL
LigandPNGBDBM50540272((+)-Malbrancheamide | CHEMBL508749)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 (DE3) cells using PNPP as substate preincubated for 5 mins followed by substrate additon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of North Carolina Greensboro

Curated by ChEMBL
LigandPNGBDBM50540271(CHEMBL4638865)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 (DE3) cells using PNPP as substate preincubated for 5 mins followed by substrate additon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of North Carolina Greensboro

Curated by ChEMBL
LigandPNGBDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 (DE3) cells using PNPP as substate preincubated for 5 mins followed by substrate additon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed