Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50010481
TargetProtein kinase C zeta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PKC in rat RBL2H3 cells assessed as inhibition of mouse anti-DNP IgE-stimulated beta-hexosaminidase release preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PKC in rat RBL2H3 cells assessed as inhibition of anti-DNP IgE-stimulated TNFalpha release preincubated for 15 mins followed by mouse a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 800nMAssay Description:Inhibition of PKC in rat RBL2H3 cells assessed as inhibition of ionomycin-stimulated beta-hexosaminidase release preincubated for 15 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PKC in rat RBL2H3 cells assessed as inhibition of ionomycin-stimulated TNFalpha release preincubated for 15 mins followed by ionomycin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50539389(CHEMBL4636684)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of mouse anti-DNP IgE-stimulated beta-hexosaminidase release preincubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50539389(CHEMBL4636684)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of anti-DNP IgE-stimulated TNFalpha release preincubated for 15 mins followed by mou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50539389(CHEMBL4636684)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of ionomycin-stimulated TNFalpha release preincubated for 15 mins followed by ionomy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50539389(CHEMBL4636684)
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of PKCbeta in rat RBL2H3 cells assessed as inhibition of ionomycin-stimulated beta-hexosaminidase release preincubated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50539389(CHEMBL4636684)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant full-length N-temrinal GST-tagged human PKC beta1 expressed in baculovirus infected Sf9 cells using TMB as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed