Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50008502
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 40nMAssay Description:Inhibition of rat lens ALR2 using methylglyoxal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 42nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 51nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 66nMAssay Description:Inhibition of human AKR1B1 expressed in Escherichia coli using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519877(CHEMBL4462469)
Affinity DataIC50: 85nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(CHEMBL1405739 | ALR2 inhibitor, 12)
Affinity DataIC50: 102nMAssay Description:Inhibition of human AKR1B1 expressed in Escherichia coli using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(CHEMBL1405739 | ALR2 inhibitor, 12)
Affinity DataIC50: 116nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519877(CHEMBL4462469)
Affinity DataIC50: 118nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519875(CHEMBL4566195)
Affinity DataIC50: 120nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(CHEMBL1405739 | ALR2 inhibitor, 12)
Affinity DataIC50: 146nMAssay Description:Inhibition of rat lens ALR2 using methylglyoxal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(CHEMBL1405739 | ALR2 inhibitor, 12)
Affinity DataIC50: 176nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 216nMAssay Description:Inhibition of rat lens ALR2 using 4-hydroxynonenal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519875(CHEMBL4566195)
Affinity DataIC50: 233nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 292nMAssay Description:Inhibition of rat lens ALR2 using 4-hydroxynonenal glutathione as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519876(CHEMBL4541343)
Affinity DataIC50: 434nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(CHEMBL1405739 | ALR2 inhibitor, 12)
Affinity DataIC50: 644nMAssay Description:Inhibition of rat lens ALR2 using 4-hydroxynonenal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519876(CHEMBL4541343)
Affinity DataIC50: 787nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(CHEMBL1405739 | ALR2 inhibitor, 12)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of rat lens ALR2 using 4-hydroxynonenal glutathione as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 5.62E+4nMAssay Description:Inhibition of human AKR1B10 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed