Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50009479
TargetAcetyl-CoA carboxylase 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50247081(CHEMBL4060253)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of mouse His-tagged ACC1 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529222(CHEMBL4528475)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human His-tagged ACC1 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50247081(CHEMBL4060253)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human His-tagged ACC1 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529224(CHEMBL4435891)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human His-tagged ACC1 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529223(CHEMBL4577890)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human His-tagged ACC1 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529222(CHEMBL4528475)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of mouse His-tagged ACC1 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529222(CHEMBL4528475)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of ACC1 in human HCT116 cells assessed as reduction in [14C]acetate uptake preincubated for 60 mins followed by [14C]acetate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50247081(CHEMBL4060253)
Affinity DataIC50: 36nMAssay Description:Inhibition of mouse His-tagged ACC2 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529223(CHEMBL4577890)
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant human His-tagged ACC2 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529224(CHEMBL4435891)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human His-tagged ACC2 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529222(CHEMBL4528475)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human His-tagged ACC2 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50247081(CHEMBL4060253)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human His-tagged ACC2 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529222(CHEMBL4528475)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse His-tagged ACC2 expressed in baculovirus infected SF9 cells using acetyl-CoA as substrate incubated for 60 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed