Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50008481
TargetE3 ubiquitin-protein ligase Mdm2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50519655(CHEMBL4574805)
Affinity DataKd:  12nMAssay Description:Binding affinity to human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 1 hr by DTT reagent based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCatenin beta-1(Mouse)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50519659(CHEMBL4577037)
Affinity DataKd:  18nMAssay Description:Binding affinity to mouse GST tagged beta catenin (133 to 665 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50519656(CHEMBL4471701)
Affinity DataIC50: 11nMAssay Description:Displacement of TMR-labelled PDI from human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells preincuabted for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50519653(CHEMBL4443840)
Affinity DataIC50: 12nMAssay Description:Displacement of TMR-labelled PDI from human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells preincuabted for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50519658(CHEMBL4534075)
Affinity DataIC50: 12nMAssay Description:Displacement of TMR-labelled PDI from human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells preincuabted for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50519660(CHEMBL4563607)
Affinity DataIC50: 12nMAssay Description:Displacement of TMR-labelled PDI from human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells preincuabted for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50519657(CHEMBL4585112)
Affinity DataIC50: 24nMAssay Description:Displacement of TMR-labelled PDI from human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells preincuabted for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50519654(CHEMBL4548664)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of TMR-labelled PDI from human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells preincuabted for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCatenin beta-1(Mouse)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50519661(CHEMBL4470546)
Affinity DataIC50: 1.52E+5nMAssay Description:Displacement of FAM-labelled GGYPECILDCHLQRVIL-NH2 from mouse GST tagged beta catenin (133 to 665 residues) expressed in Escherichia coli BL21 (DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed