Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50008267
TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517238(CHEMBL4457820)
Affinity DataIC50: 116nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517238(CHEMBL4457820)
Affinity DataIC50: 126nMAssay Description:Inhibition of KRAS G12C mutant in human MIAPaCa2 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517237(CHEMBL4473733)
Affinity DataIC50: 129nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517241(CHEMBL4467039)
Affinity DataIC50: 169nMAssay Description:Inhibition of KRAS G12C mutant in human MIAPaCa2 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517242(CHEMBL4466335)
Affinity DataIC50: 214nMAssay Description:Inhibition of KRAS G12C mutant in human MIAPaCa2 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517237(CHEMBL4473733)
Affinity DataIC50: 236nMAssay Description:Inhibition of KRAS G12C mutant in human MIAPaCa2 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517241(CHEMBL4467039)
Affinity DataIC50: 395nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517242(CHEMBL4466335)
Affinity DataIC50: 468nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517240(CHEMBL4572411)
Affinity DataIC50: 640nMAssay Description:Inhibition of KRAS G12C mutant in human MIAPaCa2 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517240(CHEMBL4572411)
Affinity DataIC50: 780nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50517239(CHEMBL4441401)
Affinity DataIC50: 4.86E+3nMAssay Description:Inhibition of KRAS G12C mutant in human MIAPaCa2 cells assessed as increase in accumulation of GDP bound KRAS G12C mutant protein incubated for 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed