Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50007415
TargetD(1A) dopamine receptor(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50509149(CHEMBL3421836)
Affinity DataEC50:  76nMAssay Description:Positive allosteric modulator activity at human D1 receptor stably expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced cAMP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50509150(LY-3154207 | Ly3154207 | Mevidalen)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at human D5 receptor transiently expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50509150(LY-3154207 | Ly3154207 | Mevidalen)
Affinity DataEC50:  3nMAssay Description:Positive allosteric modulator activity at human D1 receptor stably expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced cAMP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50509151(CHEMBL3421730)
Affinity DataEC50:  14nMAssay Description:Positive allosteric modulator activity at human D1 receptor stably expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced cAMP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50509150(LY-3154207 | Ly3154207 | Mevidalen)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human D1 receptor stably expressed in HEK293 cells assessed as induction of cAMP accumulation incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50509150(LY-3154207 | Ly3154207 | Mevidalen)
Affinity DataEC50:  2.30nMAssay Description:Positive allosteric modulator activity at human D1 receptor transiently expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Mouse)
Amri

Curated by ChEMBL
LigandPNGBDBM50509150(LY-3154207 | Ly3154207 | Mevidalen)
Affinity DataEC50:  62nMAssay Description:Positive allosteric modulator activity at mouse D1 receptor transiently expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50509150(LY-3154207 | Ly3154207 | Mevidalen)
Affinity DataIC50: 3.80E+3nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin) by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed